Apex Biotech Labs
Decoding the genome to redefine medicine.
Sequencing platforms, spatial transcriptomics, and bioinformatics pipelines trusted by 40+ pharmaceutical partners worldwide.
Where biology meets engineering.
Apex Biotech was founded in 2018 by three computational biologists from the Salk Institute, around a single conviction: that every meaningful clinical question deserves an instrument purpose-built to answer it.
Today, 120 researchers across our La Jolla and Cambridge facilities engineer microfluidic platforms that process 10,000 single-cell samples per hour. The platforms generate the high-resolution data that modern precision medicine demands — and the bioinformatics infrastructure to turn that data into decisions.
Four platforms. One pipeline.
An integrated stack engineered so each platform compounds the others — from raw sample to clinically annotated insight.
Genomic Sequencing
Long-read and short-read sequencing at scale. Custom library preparation protocols deliver clinical-grade whole genome analysis with industry-leading turnaround.
Spatial Transcriptomics
Map gene expression within intact tissue architecture. Resolve cellular heterogeneity at subcellular resolution.
Drug Target Validation
CRISPR screening libraries combined with high-content imaging to identify therapeutic targets with statistical rigor.
Bioinformatics Pipeline
Automated analysis from raw reads to actionable insights. ML-powered variant calling detects clinically relevant mutations.
Eight years. Forty partners. Three million genomes.
40+
Pharmaceutical Partners
99.97%
Sequencing Accuracy
12
FDA Submissions Supported
3.2M
Genomes Processed
End-to-end pipeline
From sample to insight.
Every project follows the same disciplined four-stage workflow — designed for traceability and reviewed against ISO 17025 quality standards.
- 1
Sample Intake
Biological samples received under chain-of-custody. LIMS-tracked from arrival to data delivery — every aliquot, every freezer, every operator.
- 2
Library Preparation
Proprietary enzymatic protocols optimize fragment size and adapter ligation for each sequencing platform and downstream application.
- 3
High-Throughput Sequencing
Samples run across our sequencer fleet with real-time quality monitoring. Adaptive loading algorithms maximize data yield per flow cell.
- 4
Bioinformatics Analysis
Automated pipelines align reads, call variants, and annotate findings against curated reference databases. Results delivered via secure portal.
Research partners
Trusted by the people advancing precision medicine.
“
Apex cut our target identification timeline from eighteen months to seven. Their spatial transcriptomics revealed tumor subpopulations our bulk sequencing completely missed.
Dr. Sarah Chen VP Oncology Research, Meridian Therapeutics
“
The bioinformatics pipeline alone is worth the partnership. Raw FASTQ files to clinically annotated variants in under seventy-two hours. Our previous vendor took three weeks.
Dr. James Okafor Director of Genomics, Pacific Northwest Medical Center
“
Three IND applications submitted using Apex's data packages. The FDA reviewers specifically called out the quality and completeness of the genomic characterization.
Dr. Maria Gonzalez Chief Scientific Officer, Lumina Rare Disease
Ready to accelerate your research?
Schedule a thirty-minute consultation with our scientific team to walk through how our platforms can advance your pipeline.